产品信息:
CAS #: 66575-29-9
Synonyms: Colforsin; 7-beta-acetoxy-8,13-epoxy-1-alpha, 6-beta, 9-alpha-trihydroxylabd-14-en-11-one;Coleonol
Appearance: White to white with yellow cast powder
Melting Point: 230-232°C 1
Molecular formula: C22H34O7
Molecular weight: 410.5 (anhydrous)
Specific Rotation: -26.19° where c = 1.68% in
chloroform at 25EC 2
Absorbance max: 210 nm (E molar = 1000)
305 nm (E molar = 50)3
Purity: Not less than 98% (HPLC)
Forskolin is a labdane diterpenoid with antihypertensive, positive inotropic, platelet aggregation inhibitory and adenylate cyclase activating properties.The activation of adenylate cyclase results in increased intracellular cyclic AMP in most tissue and cells.Sigma’s product is prepared by grinding Coleus forskohlii roots followed by extraction and then purification by silica chromatography.
产品使用指南:
Forskolin is soluble in organic solvents such as ethanol,chloroform and DMSO. Sigma routinely tests its solubility in chloroform at 50 mg/mL and observes a clear, colorless to pale yellow solution. Forskolin is soluble in water (with 2% ethanol) up to 0.2 mM by first dissolving in ethanol at 5 mg/mL and doing subsequent dilutions with water. Similar results were found with DMSO.4 Please note, however, that various solvents, including ethanol, inhibited the forskolin activation of adenylate cyclase. DMSO is recommended for preparing forskolin solutions because at concentrations of 5% or less of DMSO, there is little if any inhibition of forskolin activation.Forskolin solutions at 5 mg/mL in either ethanol or DMSO were stable for at least 6 months at room temperature per HPLC analysis.
产品保存:
粉末保存在2~8°,3年内有效;溶液保存在-20°,2年内有效。
订购信息:产品来源Sigma公司
供应商
|
货号
|
规格
|
价格
|
货期
|
|
Forskolin 溶液
|
GeneOperation
|
F6886
|
1ml 5mg/1ml
|
897元
|
现货
|
Forskolin
|
F6886
|
50mg
|
2250元
|
现货
|
|
Forskolin
|
GeneOperation
|
F6886
|
100mg
|
3960元
|
3周内
|
Forskolin
|
GeneOperation
|
F6886
|
1g
|
38000元
|
3周内
|
Forskolin
|
GeneOperation
|
F6886
|
1g*5
|
询价
|
3周内
|