白介素-17抗体

中文名称：

 白介素-17抗体 

英文名称：

 Anti-IL-17(Interleukin-17)

产品编号：

 PL031183R

免 疫 原：

 KLH conjugated synthetic peptide derived from mouse IL-17 (85-150aa)

克隆类型：

 Rabbit Polyclonal IgG 

产品规格：

 0.1mg/0.2mg

包装情况：

一支包装（原装进口、分装）

其他名称：

 Interleukin-17; CTLA 8; CTLA8; Cytotoxic T lymphocyte associated antigen 8; Cytotoxic T lymphocyte associated protein 8; Cytotoxic T lymphocyte associated serine esterase 8; IL 17A; IL17A; IL-17A; Interleukin 17; Interleukin 17A; Interleukin17; Interleukin17A.

背景介绍：

  IL17, also known as CTLA8, is a T cell derived hematopoietic cytokine. It was originally cloned from a T cell hybridoma produced by fusion of a mouse cytotoxic T cell clone and a rat T lymphoma. IL17 exhibits multiple biological activities on a variety of cells including: the induction of IL6, IL8 and GCSF production in fibroblasts; the enhancement of surface expression of ICAM 1 in fibroblasts; activation of NF kappaB and costimulation of T cell proliferation. IL17 is an approximately 16 kDa polypeptide of 136 amino acids. The precursor form of IL17 consists of 155 amino acids. To generate the mature IL17 (136 amino acids), the precursor cleaves a 19 amino acid signal peptide. Human IL17 shows approximately 62.5% amino acid homology to mouse IL17 and 58% amino acid homology to rat IL17.

交叉反应
       物 种：

 Mouse, Rat,    （Please decide the specificity by homology）