中文名称: |
兔抗人、大、小鼠、牛、羊、猪粒细胞-巨噬细胞集落刺激因子3抗体 |
英文名称: |
Anti-CSF3 |
产品编号: |
PL031023R |
免 疫 原: |
KLH conjugated synthetic peptide derived from human CSF |
克隆类型: |
Rabbit Polyclonal IgG |
产品规格: |
0.1mg/0.2mg |
产品情况: |
一支包装 |
其他名称: |
colony stimulating factor 3 (granulocyte); CSF 3; CSF beta; CSF3; Csfg; Filgrastim; GCSA; GCSF; Granulocyte colony stimulating factor; Lenograstim; Macrophage granulocyte inducer 2; MGC45931; MGI 2; Pluripoietin; Granulocyte colony Stimulating Factors 3. |
背景介绍: |
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins that regulate haematopoietic cell proliferation and differentiation. G-CSF was isolated initially as a factor supporting the growth of colonies of granulocytes in soft agar cultures. Cells of the monocyte/macrophage lineage are among the most prominent sources of G-CSF, but this factor can also be produced by normal cells of mesodermal origin, including vascular endothelial cells, fibroblasts, and mesothelial cells. Production of G-CSF can be induced in vitro in these cells by a wide variety of stimulatory agents, including LPS, TNF, IL-1, IL-3, I L-4, and IFN-Gamma. G-CSF is likely to play a role in the basal regulation of neutrophil production, and also functions as a primary regulatory factor controlling the neutrophil response to inflammatory stimuli. Furthermore, G-CSF exhibits other biological activities besides the proliferative effects, since G-CSF appears to modulate the distribution of neutrophils and progenitor cells within the body. |
交叉反应 |
Human, Mouse, Rat, Pig, Cow, Sheep, (Please decide the specificity by homology) |
特别提示: |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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