白介素4抗体(大、小鼠)

中文名称：

 白介素4抗体(大、小鼠)

英文名称：

 Anti-IL-4(Interleukin-4)mouse rat

产品编号：

 PL030581R

免 疫 原：

 KLH conjugated synthetic peptide derived from mouse IL-4C-terminus

克隆类型：

 Rabbit Polyclonal IgG

产品规格：

 0.1mg/0.2mg

产品情况：

 一支包装

其他名称：

 B cell growth factor 1; B cell IgG differentiation factor; B Cell Stimulatory Factor 1; BCGF 1; BCGF1; Binetrakin; BSF 1; BSF1; HCGF; Hodgkin’s Cell Growth Factor; IA Inducing Factor; IGG1 induction factor; IL 4; Il4e12; Interleukin 4; Interleukin 4, isoform 1; Interleukin4; Lymphocyte stimulatory factor 1; Macrophage fusion factor; Mast cell growth factor 2; MCGF2; MFF; MGC79402; Pitrakinra; T cell growth factor 2; TCGF2.

背景介绍：

 Interleukin4 is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. It is a ligand for Interleukin 4 receptor. The Interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. IL4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of natve CD4+ T cell to the Th2 type. Th2 cells produce IL4, IL5, IL10 and IL13, which tend to favor a humoral immune response while suppressing a cell mediated immune response controlled by Th1 cells. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. The second is regulating IgE and IgG1 production by B cells. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

交叉反应
       物 种：

 Mouse, Rat,（Please decide the specificity by homology）