Iclaprim 是一种新的, 有选择性的细菌二氢叶酸抑制剂, 可以抑制金黄色葡萄球菌 (MRSA) 的生长, 其 MIC90 值为 0.06 μg/mL。
Molecular Weight
354.40
354.40
Formula
C₁₉H₂₂N₄O₃
C₁₉H₂₂N₄O₃
CAS No.
192314-93-5
192314-93-5
参考文献
[1]. Schneider P, et al. Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4217-21.
[2]. Kohlhoff SA, et al. Iclaprim. Expert Opin Investig Drugs. 2007 Sep;16(9):1441-8.
[1]. Schneider P, et al. Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4217-21.
[2]. Kohlhoff SA, et al. Iclaprim. Expert Opin Investig Drugs. 2007 Sep;16(9):1441-8.
