华拓生物科技有限公司

中文名称：

英文名称：

Anti-Cyclin D2

其他名称：

CCND 2;CCND2;CyclinD2;G1/S specific cyclin D2;KIAK0002;MGC102758.

产品品牌：

Pllabs

产品编号：

PL031148R

产品规格：

0.1mg/0.2mg

产品包装：

 一支包装（原装进口、进口分装）

免 疫 原：

KLH conjugated synthetic peptide derived from the middle of human Cyclin D2

克隆类型：

Rabbit Polyclonal IgG

背景介绍：

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.

应用范围：

hu, mo, rat（Please decide the specificity by homology）

更多产品：

www.pllabs.com（加拿大PLlabs公司官网）

其他产品：

www.otwobiotech.com（华拓生物中文网）