华拓生物科技有限公司

中文名称：

 载脂蛋白A1抗体

英文名称：

 Anti-Apo-a1/Apo A1 (Apolipoprotein A-1; APOA1 protein )

产品编号：

 PL030849R

免 疫 原：

 KLH conjugated synthetic peptide derived from human  APOA1 C-terminus

克隆类型：

 Rabbit Polyclonal IgG

产品规格：

 0.1mg/0.2mg

包装情况：

 一支包装

其他名称：

 Apolipoprotein A I; Apolipoprotein A 1; Apo AI; ApoA I; APOA1; APOA1/APOC3 fusion gene; Apo A1; Apo-A1; Apolipoprotein A I precursor; Apolipoprotein AI; Apolipoprotein of high density lipoprotein; ApolipoproteinAI; Brp14; Ltw1; Lvtw1; MGC117399; Sep1; Sep2.

背景介绍：

 Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.

交叉反应
       物 种：

 Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit,  （Please decide the specificity by homology）