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| 产品： |
浏览次数：123兔抗人乳头瘤病毒16型E7抗体 |
| 品牌： |
pllabs |
| 单价： |
面议 |
| 最小起订量： |
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| 供货总量： |
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| 发货期限： |
自买家付款之日起 3 天内发货 |
| 有效期至： |
长期有效 |
| 最后更新： |
2016-05-24 10:10 |
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| 中文名称： |
兔抗人乳头瘤病毒16型E7抗体 |
| 英文名称： |
Anti-HPV16 E7 protein (Human papillomavirus type 16 E7) |
| 产品品牌： |
P llabs |
| 产品编号： |
PL030714R |
| 产品规格： |
0.2mg |
| 克隆类型： |
Rabbit Polyclonal IgG |
| 免 疫 原： |
KLH conjugated synthetic peptide derived from HPV16 E7 protein |
| 背景介绍： |
Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with pvalue="53" hasspace="True" negative="False" numbertype="1" tcsc="0" w:st="on">53 in vitro. |
| 别 名： |
E7; Human Papilloma Virus; Human papillomavirus type 16 E7; Human papillomavirus type 16 E7; Protein E7; Human Papillomavirus 16 (E7); HPV16 E7; E7 protein (HPV16); VE7_HPV16. |
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