中文名称：

多药耐药相关蛋白2抗体

英文名称：

Anti-MRP2 (multidrug resistance-associated protein2)

产品品牌：

Pllabs

产品编号：

PL031092R

产品规格：

0.1mg/0.2mg

产品包装：

一支包装（原装进口、进口分装）

其他名称：

multidrug resistance-associated protein2; ABC30; ABCC2; ATP binding cassette sub family C (CFTR/MRP) member 2; ATP binding cassette subfamily C member 2; Canalicular multidrug resistance protein; Canalicular multispecific organic anion transporter 1; CMOAT; CMOAT1; cMRP; DJS; KIAA1010; MRP 2; Multidrug resistance associated protein 2.

免 疫 原：

KLH conjugated synthetic peptide derived from human MRP2 N-terminus

背景介绍：

multidrug resistance-associated protein 2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. Belongs to the ABC transporter family.

应用范围：

hu, mo, rat（Please decide the specificity by homology）

更多产品：

www.pllabs.com（加拿大PLlabs公司官网）

其他产品：

www.otwobiotech.com（华拓生物中文网）